Who are candidates for K-ras Mutation Detection?
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If the candidate meets the following criteria, K-ras Mutation Detection test could be available:
» Patient has been diagnosed with metastatic colorectal cancer;
» Patient has failed on fluoropyrimidine-, oxaliplatin-, and irinotecan-containing
chemotherapy regimens;
» Patient will be prescribed Vectibix™ if the results of the K-ras test indicate the
tumor is non-mutated (wile-type) K-ras.Other indications when K-ras Mutation Detection would be helpful include:
» Patients currently treated with Erbitux® (cetuximab) or Vectibix™ (panitumumab) for colorectal cancer or before
beginning Erbitux or Vectibix treatment;» Patients with lung cancer under treatment with tyrosine kinase inhibitors such as Iressa™ (AstraZeneca) or Tarceva™
(Roche/OSI Pharmaceuticals).Visit the Colorectal Cancer Coalition website for more information.
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Mount Sinai Services 600 University Ave. Toronto, Ontario Canada M5G 1X5 |
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