Histology Research Services
MOUNT SINAI SERVICES offers a full range of routine and customized histology services, operating under GLP practices. MSS specializes in all aspects of histopathology, immunohistochemistry, and image analysis for both animal and human tissue.
MSS’ core strength is our understanding of the experimental design, as well as our extensive experience in the development and implementation of many different methodologies utilizing histochemical and immunohistochemical techniques. MSS can provide researchers with input at the early planning phase of an experiment, as well as perform histology at any stage of a project, customized to each client’s specific needs.
Histology Services
Processing:
- Paraffin
- Plastic/Resin
- Frozen tissue
Cutting and Staining:
- Soft tissue
- Hard tissue (e.g. tissue implanted with stents and undecalcified bone)
- Whole mount preparation and cutting
Tissue Microarrays:
- Construction
- Cutting and staining
Staining Procedures:
- H&E
- Special stains
- Whole mount staining
- In situ hybridization/FISH staining
- RNA and DNA studies
Immunohistochemistry:
- Optimization of new antibodies
- Staining of routine and new antibodies (paraffin, TMA’s and plastic )
- Immunofluorescence staining
- Double staining
Imaging and Morphometry Services
- Muscle, bone and stent morphometry
- Digital imaging of slides using Brightfield and Fluorescence Microscopy including TMA imaging
- Image analysis
- Pathological scoring/analysis and report generation
Advanced Bioimaging
- Analytic scanning electron microscopy (SEM)
- Analytical transmission electron microscopy (TEM)
- Scanning probe microscopy
- Confocal microscopy
- Special specimen preparation, including cryopreparation
Consultation Services
- Project feasibility assessment
- Research project development and management
- Quality management
- Development of standard operating procedures (SOP’s)
- Project coordination with academia and industry (including compliance with FDA)